Diapositiva PPT

• Human study using ESRD patients

• In vivo changes in pH, osmolality, solute flux included

• In vivo biological mediators involved (e.g., cytokine network)

Method

Advantages

1.

Infuse test solution i.p.

2.

Dwell for e.g. 30 minutes

3.

Drain and isolate PMØ

4.

Assay cells for function

The acute Ex vivo approach to measure cell function

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